Cystatin C detection reagent (immunofluorescence chromatography) (CysC)
CysC overview
Cysteinase proteinase inhibitor (CPI) is named cystatin C. Cystatin C in circulation is removed only through glomerular filtration, which is an endogenous marker reflecting the change of glomerular filtration rate, and reabsorbed in the proximal convoluted tubules, but is metabolized and decomposed completely after reabsorption, and does not return to blood. Therefore, the concentration of cystatin C in the blood is determined by glomerular filtration rate, and does not depend on any external factors, such as gender, age and diet, It is an ideal endogenous marker reflecting the change of glomerular filtration rate.
CysC performance index
| Detection range | sample size | Sample type | Test time |
| 0.2~8mg/L | 10μl | Whole blood / serum / plasma | 15min |
Clinical significance of CysC
- The most ideal endogenous marker for GFR reaction
- Early diagnosis and monitoring of renal diseases
- Renal function assessment of AKI high risk population
- The detection of renal function in the process of chronic disease management
Sensitivity comparison of cystatin C and serum creatinine in the evaluation of GFR
| | Cystatin C | Cystatin C |
| creatinine | |
| GFR(mL/min/1.73m2) | >89 | 60-89 | 30-59 | 15-29 | <15 |
| CKD stage | 1 | 2 | 3 | 4 | 5 |
| | GFR normal / elevated kidney damage | Mild renal insufficiency | moderate renal insufficiency | Severe renal insufficiency | End stage renal disease (ESRD) |
Application Department
Internal medicine, pediatrics, orthopedics, cardiology, gynecology, obstetrics and Gynecology, emergency, ICU, Nephrology, oncology, surgery, etc
Clinical comparison of CysC
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.
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